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Human CCL26/Eotaxin-3 ELISA Kit Plate

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Product Details

Standard - EK1150.jpg

Brand

MultiSciences

CatNum

70-EK1150

Product Name

Human CCL26/Eotaxin-3 ELISA Kit

Customs Name

Human CCL26/Eotaxin-3 ELISA Kit

Application

ELISA

Reactivity

Human

Assay Type

Sandwich ELISA

Suitable Sample Type

serum, plasma, cell culture supernates

Format

96-well strip plate

Storage

4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)

Shipping Condition

4℃

Sample Volume

20 μl

Sensitivity

1.44 pg/ml

Standard Curve Range

15.63 - 1000 pg/ml

Spike Recovery Range

81 % - 120 %

Mean Spike Recovery

0.94

CV of Intra plate

2.2 % - 4.0 %

CV of Inter plate

3.0 % - 3.5 %

Components

96-well polystyrene microplate coated with a monoclonal antibody against Eotaxin-3

Human Eotaxin-3 Standard, lyophilized

Eotaxin-3 Detect Antibody

Standard Diluent

Streptavidin-HRP

Assay Buffer (10×)

Substrate (TMB)

Stop Solution

Washing Buffer (20×)

Plate Covers

Describtion

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human Eotaxin-3. The Human CCL26/Eotaxin-3 ELISA is for research use only. Not for diagnostic or therapeutic procedures.

Chemokine (C-C motif) ligand 26 (CCL26) is a small cytokine belonging to the CC chemokine family that is also called Eotaxin-3, Macrophage inflammatory protein 4-alpha (MIP-4α), Thymic stroma chemokine-1 (TSC-1), and IMAC. It is expressed by several tissues including heart, lung and ovary, and in endothelial cells that have been stimulated with the cytokine interleukin 4. Eotaxin-3 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3. Eotaxin-3, along with Eotaxin-1 and Eotaxin-2, selectively activates the CC chemokine receptor 3 (CCR3). The Eotaxin-3-CCR3 interaction may play an important role in allergic diseases such as atopic dermatitis and bronchial asthma.

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