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Human CEACAM5/CD66e Sandwich ELISA Kit

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Product Details

Standard - EK1229.jpg


BrandMultiSciences
CatNum70-EK1229
ProductNameHuman CEACAM5/CD66e ELISA Kit
CustomsNameHuman CEACAM5/CD66e ELISA Kit
ApplicationELISA
ReactivityHuman
Assay TypeSandwich ELISA
Suitable Sample Typeserum, plasma, cell culture supernates
Format96-well strip plate
Storage4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition4℃
Sample Volume10 μl (prediluted)
Sensitivity24.03 pg/ml
Standard Curve Range468.75 - 30000 pg/ml
Spike Recovery Range-
Mean Spike Recovery-
CV of Intra plate3.7 - 4.9 %
CV of Inter plate2.4 - 3.3 %
Components96-well polystyrene microplate coated with a monoclonal antibody against CEACAM5
Human CEACAM5 Standard, lyophilized
CEACAM5 Detect Antibody
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers
DescribtionThis assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human CEACAM5. The Human CEACAM5/CD66e ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5), also known as CD66e, belongs to the large family of CEACAM and pregnancy specific glycoproteins. It is expressed primarily by epithelial cells, consists of an N-terminal Ig like V-type domain followed by six Ig-like C2-type domains and a GPI anchor. CEACAM5 is restricted to the apical face of intestinal epithelial cells in the adult but is more diffuse during embryonic development and in tumors. CEACAM5 is upregulated in a wide variety of human tumors and is a commonly used cancer marker. It promotes tumor cell migration, invasion, adhesion, and metastasis. CEACAM5 also contributes to tumor formation by maintaining cellular proliferation in the presence of differentiation stimuli. In addition, CEACAM5 is identified as the host receptor for the Dr family of adhesins of E.Coli, and the binding of E.coli Dr adhesins leads to dissociation of the CEACAM5 homodimer.

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