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Human CTGF ELISA Assay Kit

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Product Details

Standard - EK198(001).jpg


BrandMultiSciences
CatNum70-EK198
ProductNameHuman CTGF ELISA Kit
CustomsNameHuman CTGF ELISA Kit
ApplicationELISA
ReactivityHuman
Assay TypeSandwich ELISA
Suitable Sample Typeserum, plasma, cell culture supernates
Format96-well strip plate
Storage4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition4℃
Sample Volume50 μl
Sensitivity2.31 pg/ml
Standard Curve Range62.50 - 4000 pg/ml
Spike Recovery Range88 % - 115 %
Mean Spike Recovery1.03
CV of Intra plate6.3 % - 7.5 %
CV of Inter plate4.9 % - 6.7 %
Components96-well polystyrene microplate coated with a monoclonal antibody against CTGF
Human CTGF Standard, lyophilized
CTGF Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
washing Buffer (20×)
Plate Covers
DescribtionThis assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human CTGF. The Human CTGF ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Connective tissue growth factor (CTGF, CCN2) is a matricellular protein of the CCN family. has The extracellular part of CTGF includes four conserved, cysteine-rich domains: the insulin-like growth factor binding protein (IGFBP) domain, the von Willebrand type C repeats (vWC) domain, the thrombospondin type 1 repeat (TSR) domain, and a C-terminal domain (CT) with a cysteine knot motif. CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, and tissue wound repair. It is thought that CTGF can cooperate with TGF-β to induce sustained fibrosis and to exacerbate extracellular matrix production in association other fibrosis-inducing conditions.
Monitoring of CTGF levels in serum provides more detailed insights in several pathological situations such as malignancies, diabetic nephropathy, retinopathy, fibrosis, arthritis, pancreatic cancer and cardiovascular diseases.

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