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Human EpCAM/CD326 Antibody ELISA Kit

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Product Details

Standard - EK1170.jpg


Brand

MultiSciences

Cat Num

70-EK1170

Product Name

Human EpCAM/CD326 ELISA Kit

Customs Name

Human EpCAM/CD326 ELISA Kit

Application

ELISA

Reactivity

Human

Assay Type

Sandwich ELISA

Suitable Sample Type

serum, plasma, cell culture supernates

Format

96-well strip plate

Storage

4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened)

Shipping Condition

4℃

Sample Volume

20 μl

Sensitivity

8.39 pg/ml

Standard Curve Range

62.50 - 4000 pg/ml

Spike Recovery Range

74 % - 102 %

Mean Spike Recovery

0.85

CV of Intra plate

3.8 % - 4.7 %

CV of Inter plate

3.4 % - 9.4 %

Components

96-well polystyrene microplate coated with a monoclonal antibody against EpCAM
Human EpCAM Standard, lyophilized
EpCAM Detect Antibody
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers

Describtion

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human EpCAM. The Human EpCAM/CD326 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Epithelial cell adhesion molecule (EpCAM), also known as CD326, is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, EpCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since EpCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, EpCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies.

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