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Human EPOR Cytokine ELISA Kit

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Product Details

Standard - EK1181.jpg


Brand

MultiSciences

Cat Num

70-EK1181

Product Name

Human EPOR ELISA Kit

Customs Name

Human EPOR ELISA Kit

Application

ELISA

Reactivity

Human

Assay Type

Sandwich ELISA

Suitable Sample Type

serum, plasma, cell culture supernates

Format

96-well strip plate

Storage

4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened)

Shipping Condition

4℃

Sample Volume

50 μl

Sensitivity

0.42 pg/ml

Standard Curve Range

7.81 - 500 pg/ml

Spike Recovery Range

87 % - 118 %

Mean Spike Recovery

1.05

CV of Intra plate

2.5 % - 3.0 %

CV of Inter plate

1.8 % - 3.1%

Components

96-well polystyrene microplate coated with a monoclonal antibody against EPOR
Human EPOR Standard, lyophilized
EPOR Detect Antibody
Standard Diluent
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers

Describtion

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human EPOR. The Human EPOR ELISA is for research use only. Not for diagnostic or therapeutic procedures.
The erythropoietin receptor (EPOR) is a protein that in humans is encoded by the EPOR gene. EPOR is a 59 kDa peptide and is a member of the cytokine receptor family. The cytoplasmic domains of the EPOR contain a number of phosphotyrosines that are phosphorylated by Jak2 and serve as docking sites for a variety of intracellular pathway activators and Stats. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Overproduction of red blood cells increases a chance of adverse cardiovascular event, such as thrombosis and stroke. EPOR signaling prevents neuronal death and ischemic injury.

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