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Human FGFR2/CD332 Protein A ELISA Kit

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Product Details

Standard - EK1242.jpg

BrandMultiSciences
CatNum70-EK1242
ProductNameHuman FGFR2/CD332 ELISA Kit
CustomsNameHuman FGFR2/CD332 ELISA Kit
ApplicationELISA
ReactivityHuman
Assay TypeSandwich ELISA
Suitable Sample Typeserum, plasma, cell culture supernates
Format96-well strip plate
Storage4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition4℃
Sample Volume50 μl
Sensitivity4.14 pg/ml
Standard Curve Range31.25 - 2000 pg/ml
Spike Recovery Range74 % - 124 %
Mean Spike Recovery1.07
CV of Intra plate3.0 % - 7.6 %
CV of Inter plate5.1 % - 6.8 %
Components96-well polystyrene microplate coated with a monoclonal antibody against FGFR2
Human FGFR2 Standard, lyophilized
FGFR2 Detect Antibody
Standard Diluent
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers
DescribtionThis assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human FGFR2. The Human FGFR2/CD332 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Fibroblast growth factor receptor 2 (FGFR2), also known as CD332, is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. This protein consists of an extracellular region composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
FGFR2 has important roles in embryonic development and tissue repair, especially bone and blood vessels. Mutations are associated with numerous medical conditions that include abnormal bone development (e.g. craniosynostosis syndromes) and cancer.

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