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Human GM-CSF ELISA Kit Antibody ELISA Kit

Welcome to buy the high quality and sanitary human gm-csf elisa kit antibody elisa kit with our professional manufacturers and suppliers. We can assure of you of the high quality and competitive price of our ELISA kit for procedure.

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Product Details

Standard - EK163.jpg

Brand

96-well strip plate

CatNum

4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)

Product Name

4℃

Customs Name

20 μl

Application

4.76 pg/ml

Reactivity

7.81 - 500 pg/ml

Assay Type

97 % - 110 %

Suitable Sample Type

1.04

Format

2.5 % - 2.9 %

Storage

3.7 % - 4.9 %

Shipping Condition2015/4/1
Sample Volume

MultiSciences

Sensitivity

70-EK163

Standard Curve Range

Human GM-CSF ELISA Kit

Spike Recovery Range

Human GM-CSF ELISA Kit

Mean Spike Recovery

ELISA

CV of Intra plate

Human

CV of Inter plate

Sandwich ELISA

Release Dateserum, plasma, cell culture supernates
Components

96-well polystyrene microplate coated with a monoclonal antibody against GM-CSF

Human GM-CSF Standard, lyophilized

GM-CSF Detect Antibody

Standard Diluent

Streptavidin-HRP

Assay Buffer (10×)

Substrate (TMB)

Stop Solution

washing Buffer (20×)

Plate Covers

Describtion

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human GM-CSF. The Human GM-CSF ELISA is for research use only. Not for diagnostic or therapeutic procedures.

Granulocyte-macrophage colony stimulating factor (GM-CSF) is a cytokine that functions as a white blood cell growth factor. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. cDNAs for both mouse and human GM-CSF encode precursor proteins with a 17 amino acid (aa) signal peptide that is cleaved toform mature proteins with 124 and 127 aa residues, respectively. GM-CSF signals via signal transducer and activator of transcription, STAT5. In macrophages, it has also been shown to signal via STAT3. Although GM-CSF was initially characterized by its ability to stimulate neutrophil, monocyte/macrophage, and eosinophil colony formation, it has since been shown that it has additional activities on hematopoietic, as well as non-hematopoietic lineage cells. GM-CSF is manufactured using recombinant DNA technology and is marketed as a protein therapeutic called molgramostim or, when the protein is expressed in yeast cells, sargramostim. It is used as a medication to stimulate the production of white blood cells and thus prevent neutropenia following chemotherapy. GM-CSF has also recently been evaluated in clinical trials for its potential as a vaccine adjuvant in HIV-infected patients. The preliminary results have been promising, but GM-CSF is not presently FDA-approved for this purpose.

Increased levels of GM-CSF have been reported in the serum of some cancer patients, including patients with lung cancer and patients with acute myelogenous leukemia. GM-CSF has also been reported to be increased in the peripheral blood of bronchial asthma patients and in extracts of psoriatic scales.

Welcome to buy the high quality and sanitary human gm-csf elisa kit antibody elisa kit with our professional manufacturers and suppliers. We can assure of you of the high quality and competitive price of our ELISA kit for procedure.

Inquiry