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Human Granulin/GRN enzyme immunoassay Kit

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Product Details

Standard - EK1184.jpg



Cat Num


Product Name

Human Granulin/GRN ELISA Kit

Customs Name

Human Granulin/GRN ELISA Kit





Assay Type

Sandwich ELISA

Suitable Sample Type

serum, plasma, cell culture supernates


96-well strip plate


4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened)

Shipping Condition


Sample Volume

100 μl (prediluted)


10.81 pg/ml

Standard Curve Range

125 - 8000 pg/ml

Spike Recovery Range

92 % - 135 %

Mean Spike Recovery


CV of Intra plate

3.3 % - 4.3 %

CV of Inter plate

3.9 % - 4.8 %


96-well polystyrene microplate coated with a monoclonal antibody against GRN
Human GRN Standard, lyophilized
GRN Detect Antibody
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers


This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human GRN. The Human Granulin/GRN ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Granulin is a protein that in humans is encoded by the GRN gene. The precursor protein, progranulin, is also called PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling.
The human liver fluke contributes to the development of bile duct (liver) cancer by secreting a granulin-like growth hormone. Mutations in the GRN gene have been implicated in up to 25% of frontotemporal lobar degeneration, inherited in an autosomal dominant fashion with high penetrance.

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