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Human IL-21 ELISA Kit Distributor

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Product Details

Standard - EK121.jpg


BrandMultiSciences
CatNum70-EK121
ProductNameHuman IL-21 ELISA Kit
CustomsNameHuman IL-21 ELISA Kit
ApplicationELISA
ReactivityHuman
Assay TypeSandwich ELISA
Suitable Sample Typeserum, plasma, cell culture supernates
Format96-well strip plate
Storage4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition4℃
Sample Volume50 μl
Sensitivity11.99 pg/ml
Standard Curve Range62.50 - 4000 pg/ml
Spike Recovery Range87 % - 112 %
Mean Spike Recovery1.02
CV of Intra plate4.5 % - 5.6 %
CV of Inter plate7.2 % - 7.8 %
Components96-well polystyrene microplate coated with a monoclonal antibody against IL-21
Human IL-21 Standard, lyophilized
IL-21 Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
washing Buffer (20×)
Plate Covers
DescribtionThis assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IL-21. The Human IL-21 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Interleukin-21 (IL-21) is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells that can destroy virally infected or cancerous cells.This cytokine induces cell division/proliferation in its target cells. IL-21 is expressed in activated human CD4+ T cells but not in most other tissues.In addition, IL-21 expression is up-regulated in Th2 and Th17 subsets of T helper cells, as well as T follicular cells. Furthermore IL-21 is expressed in NK T cells regulating the function of these cells.
IL-21 has pathologic function in immune-inflammatory diseases. Data suggest the existence of a positive autocrine loop that could help to amplify and stabilize IL-21-driven, T cell-mediated responses. Moreover, it has antitumour activity and may have a role in the development of autoimmunity. IL-21 may have therapeutic potentials as an antitumor agent in the clinic.


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