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Human IL-23 ELISA Kit Distributor

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Product Details

Standard - EK123.jpg


BrandMultiSciences
CatNum70-EK123
ProductNameHuman IL-23 ELISA Kit
CustomsNameHuman IL-23 ELISA Kit
ApplicationELISA
ReactivityHuman
Assay TypeSandwich ELISA
Suitable Sample Typeserum, plasma, cell culture supernates
Format96-well strip plate
Storage4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition4℃
Sample Volume50 μl
Sensitivity1.82 pg/ml
Standard Curve Range31.25 - 2000 pg/ml
Spike Recovery Range86 % - 110 %
Mean Spike Recovery0.99
CV of Intra plate3.4 % - 5.3 %
CV of Inter plate3.4 % - 4.8 %
Components96-well polystyrene microplate coated with a monoclonal antibody against IL-23
Human IL-23 Standard, lyophilized
IL-23 Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
washing Buffer (20×)
Plate Covers
DescribtionThis assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IL-23. The Human IL-23 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Interleukin 23 (IL-23) is a heterodimeric cytokine that is related to IL-12. IL-23 is a heterodimeric cytokine composed of an IL-12p40 subunit that is shared with IL-12 and the IL-23p19 subunit. A functional receptor for IL-23 (the IL-23 receptor) has been identified and is composed of IL-12Rβ1 and IL-23R. Human IL-23 has biological properties which are less distinct from human IL-12; human IL-23 induces proliferation of memory T cells and induces moderate levels of IFN-γ production by naïve and memory T cells, as compared to IL-12.
IL-23 effects on IL-17-producing T cells may also enhance the development of several models of autoimmune disease including experimental allergic encephalomyelitis (EAE), collagen-induced arthritis (CIA), colitis, and diabetes. IL-23 may also play a role in increased tumor growth associated with chronic inflammation. In humans, IL-23 has been found upregulated in several pathologies with dysregulated immune function including psoriasis, Crohn's disease, and multiple sclerosis.


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