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96 Well Mouse IL-17A ELISA Kit

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Product Details

Standard - EK217.jpg

BrandMultiSciences
CatNum70-EK2172
ProductNameMouse IL-17A ELISA Kit
CustomsNameMouse IL-17A ELISA Kit
ApplicationELISA
ReactivityMouse
Assay TypeSandwich ELISA
Suitable Sample Typeserum, plasma, cell culture supernates
Format96-well strip plate
Storage4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition4℃
Sample Volume20 μl
Sensitivity0.26 pg/ml
Standard Curve Range31.25 - 2000 pg/ml
Spike Recovery Range91 % - 115 %
Mean Spike Recovery1.01
CV of Intra plate2.8 % - 5.6 %
CV of Inter plate4.2 % - 8.4 %
Components96-well polystyrene microplate coated with a monoclonal antibody against IL-17A
Mouse IL-17A Standard, lyophilized
IL-17A Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
washing Buffer (20×)
Plate Covers
DescribtionThis assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-17A. The Mouse IL-17A ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Interleukin 17 (IL-17), also known as IL-17A and CTLA-8, is a homodimeric cytokine of about 32 kDa. IL-17 is a cytokine that acts as a potent mediator in delayed-type reactions by increasing chemokine production in various tissues to recruit monocytes and neutrophils to the site of inflammation, similar to IFN-γ. IL-17 is produced by T-helper cells and is induced by IL-23 which results in destructive tissue damage in delayed-type reactions. IL-17 as a family functions as a proinflammatory cytokine that responds to the invasion of the immune system by extracellular pathogens and induces destruction of the pathogen's cellular matrix. IL-17 acts synergistically with TNF and IL-1.
IL-17 family has been linked to many immune/autoimmune related diseases including rheumatoid arthritis, asthma, lupus, allograft rejection, anti-tumour immunity and recently Psoriasis.Increased levels of IL-17 have been associated with several conditions, including airway inflammation, rheumatoid arthritis, intraperitoneal abscesses and adhesions, inflammatory bowel disease, allograft rejection, psoriasis, cancer and multiple sclerosis.
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