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96 Wells Mouse IL-4 ELISA Kit

Welcome to buy the high quality and sanitary 96 wells mouse il-4 elisa kit with our professional manufacturers and suppliers. We can assure of you of the high quality and competitive price of our ELISA kit for procedure.

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Product Details

Standard - EK204.jpg

BrandMultiSciences
CatNum70-EK204
Product NameMouse IL-4 ELISA Kit
Customs NameMouse IL-4 ELISA Kit
ApplicationELISA
ReactivityMouse
Assay TypeSandwich ELISA
Suitable Sample Typeserum, plasma, cell culture supernates
Format96-well strip plate
Storage4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition4℃
Sample Volume20 μl
Sensitivity0.34 pg/ml
Standard Curve Range7.81 - 500 pg/ml
Spike Recovery Range93 % - 106 %
Mean Spike Recovery1
CV of Intra plate6.8 % - 8.3 %
CV of Inter plate3.5 % - 6.6 %
Release Date2016/8/20
Components96-well polystyrene microplate coated with a monoclonal antibody against Mouse IL-4
Mouse IL-4 Standard, lyophilized
Mouse IL-4 Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
washing Buffer (20×)
Plate Covers
DescribtionThis assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-4. The Mouse IL-4 ELISA is for research use only. Not for diagnostic or therapeutic procedures.

Interleukin 4 (IL-4) is an approximately 18-20 kDa monomeric cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Mouse IL-4 is synthesized as a 140 amino acid (aa) precursor with a 20 aa signal sequence and a 120 aa mature chain and mature mouse IL-4 shares 43%, and 63% aa sequence identity with human and rat IL-4.

IL-4 is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4 in a positive feedback loop. The cell that initially produces IL-4, thus inducing Th0 differentiation, has not been identified, but recent studies suggest that basophils may be the effector cell. It is closely related and has functions similar to IL-13.

IL-4 also has been shown to drive mitogenesis, dedifferentiation, and metastasis in rhabdomyosarcoma. IL-4, along with other Th2 cytokines, is involved in the airway inflammation observed in the lungs of patients with allergic asthma.

Welcome to buy the high quality and sanitary 96 wells mouse il-4 elisa kit with our professional manufacturers and suppliers. We can assure of you of the high quality and competitive price of our ELISA kit for procedure.

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