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Mouse CCL2/MCP-1 Protein A ELISA Kit

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Product Details

Standard - EK287.jpg

BrandMultiSciences
CatNum70-EK287
ProductNameMouse CCL2/MCP-1 ELISA Kit
CustomsNameMouse CCL2/MCP-1 ELISA Kit
ApplicationELISA
ReactivityMouse
Assay TypeSandwich ELISA
Suitable Sample Typeserum, plasma, cell culture supernates
Format96-well strip plate
Storage4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition4℃
Sample Volume20 μl
Sensitivity20.54 pg/ml
Standard Curve Range156.25 - 10000 pg/ml
Spike Recovery Range89 % - 113 %
Mean Spike Recovery1
CV of Intra plate3.3 % - 4.6 %
CV of Inter plate3.8 % - 4.1 %
Components96-well polystyrene microplate coated with a monoclonal antibody against CCL2
Mouse CCL2 Standard, lyophilized
CCL2 Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
washing Buffer (20×)
Plate Covers
DescribtionThis assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse CCL2. The Mouse CCL2/MCP-1 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemotactic protein 1 (MCP1), is a small cytokine that belongs to the CC chemokine family. CCL2 is anchored in the plasma membrane of endothelial cells by glycosaminoglycan side chains of proteoglycans and is primarily secreted by monocytes, macrophages and dendritic cells. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection.
CCL2 is implicated in pathogeneses of several diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis and atherosclerosis. CCL2 is involved in the neuroinflammatory processes that take place in the various diseases of the central nervous system, which are characterized by neuronal degeneration.
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