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Mouse CCL22/MDC Antibody ELISA Kit

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Product Details

Standard - EK2216.jpg

BrandMultiSciences
CatNum70-EK2216
ProductNameMouse CCL22/MDC ELISA Kit
CustomsNameMouse CCL22/MDC ELISA Kit
ApplicationELISA
ReactivityMouse
Assay TypeSandwich ELISA
Suitable Sample Typeserum, plasma, cell culture supernates
Format96-well strip plate
Storage4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition4℃
Sample Volume20 μl
Sensitivity4.07 pg/ml
Standard Curve Range31.25 - 2000 pg/ml
Spike Recovery Range76 % - 92 %
Mean Spike Recovery0.84
CV of Intra plate3.4 % - 5.1 %
CV of Inter plate3.6 % - 5.8 %
Components96-well polystyrene microplate coated with a monoclonal antibody against CCL22
Mouse CCL22 Standard, lyophilized
CCL22 Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers
DescribtionThis assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse CCL22. The MouseCCL22/MDC ELISA is for research use only. Not for diagnostic or therapeutic procedures.
The chemokine (C-C motif) ligand 22 (CCL22), also known as macrophage-derived chemokine (MDC), is a member of the CC chemokine family. Cells known to express CCL22 include B cells, microglia, dendritic cells and macrophages, monocytes, IFN-γ-activated keratinocytes, colonic columnar epithelium, CD4+ T cells, thymic medullary epithelium (Hassal’s corpuscles), and activated NK cells.
CCL22 plays an important role in lymphocyte migration. CCL22 is a potent chemoattractant for cell types including dendritic cells, thymocytes, and activated NK cells. CCL22 produced by antigen-presenting dendritic cells chemoattracts CCR4-bearing activated (or memory) T cells to enhance immune responses and increase effector functions. Additional functions reported for CCL22 include the activation of platelet function and inhibition of synaptic transmission between hippocampal neurons.
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