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Mouse IL-16 Protein A ELISA Kit

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Product Details

Standard - EK216.jpg

BrandMultiSciences
CatNum70-EK216
ProductNameMouse IL-16 ELISA Kit
CustomsNameMouse IL-16 ELISA Kit
ApplicationELISA
ReactivityMouse
Assay TypeSandwich ELISA
Suitable Sample Typeserum, plasma, cell culture supernates
Format96-well strip plate
Storage4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition4℃
Sample Volume10 μl
Sensitivity0.47 pg/ml
Standard Curve Range7.81 - 500 pg/ml
Spike Recovery Range91 % - 107 %
Mean Spike Recovery0.98
CV of Intra plate3.9 % - 5.6 %
CV of Inter plate4.4 % - 5.9 %
Components96-well polystyrene microplate coated with a monoclonal antibody against CXCL1
Mouse CXCL1 Standard, lyophilized
CXCL1 Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers
DescribtionThis assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-16. The Mouse IL-16 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Interleukin 16 (IL-16) is a cytokine that is released by a variety of cells (including lymphocytes and some epithelial cells) that has been characterized as a chemoattractant for certain immune cells expressing the cell surface molecule CD4. IL-16 was originally described as a factor that could attract activated T cells in humans, it was previously called lymphocyte chemoattractant factor (LCF). Since then, IL-16 has been shown to recruit and activate many other cells expressing the CD4 molecule, including monocytes, eosinophils, and dendritic cells. The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4.
IL-16 expression has been linked to inflammation processes in asthma, rheumatoid arthritis, systemic lupus erythematosus, colitis, atopic dermatitis, and multiple sclerosis. For example, the expression of IL-16 directly correlates with the number of infiltrating CD4+ T cells in asthmatic epithelium.
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