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Mouse IL-21 ELISA Kit Distributor

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Product Details

Standard - EK221.jpg


BrandMultiSciences
CatNum70-EK221
ProductNameMouse IL-21 ELISA Kit
CustomsNameMouse IL-21 ELISA Kit
ApplicationELISA
ReactivityMouse
Assay TypeSandwich ELISA
Suitable Sample Typeserum, plasma, cell culture supernates
Format96-well strip plate
Storage4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition4℃
Sample Volume10 μl
Sensitivity0.58 pg/ml
Standard Curve Range31.25 - 2000 pg/ml
Spike Recovery Range85 % - 114 %
Mean Spike Recovery0.96
CV of Intra plate3.0 % - 5.5 %
CV of Inter plate3.5 % - 6.1 %
Components96-well polystyrene microplate coated with a monoclonal antibody against IL-21
Mouse IL-21 Standard, lyophilized
IL-21 Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
washing Buffer (20×)
Plate Covers
DescribtionThis assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse 21. The Mouse IL-21 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Interleukin-21 (IL-21) is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells that can destroy virally infected or cancerous cells. This cytokine induces cell division/proliferation in its target cells. IL-21 is
expressed in activated human CD4+ T cells but not in most other tissues. In addition, IL-21 expression is up-regulated in Th2 and Th17 subsets of T helper cells, as well as T follicular cells. Furthermore IL-21 is expressed in NK T cells regulating the function of these cells.
IL-21 has pathologic function in immune-inflammatory diseases. Data suggest the existence of a positive autocrine loop that could help to amplify and stabilize IL-21-driven, T cell-mediated responses. Moreover, it has antitumour activity and may have a role in the development of autoimmunity. IL-21 may have therapeutic potentials as an antitumor agent in the clinic.
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