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Mouse ST2/IL-33R Protein A ELISA Kit

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Product Details

Standard - EK2163.jpg

BrandMultiSciences
CatNum70-EK2163
ProductNameMouse ST2/IL-33R ELISA Kit
CustomsNameMouse ST2/IL-33R ELISA Kit
ApplicationELISA
ReactivityMouse
Assay TypeSandwich ELISA
Suitable Sample Typeserum, plasma, cell culture supernates
Format96-well strip plate
Storage4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition4℃
Sample Volume10 μl
Sensitivity0.27 pg/ml
Standard Curve Range62.50 - 4000 pg/ml
Spike Recovery Range----
Mean Spike Recovery----
CV of Intra plate3.9 % - 4.8 %
CV of Inter plate3.6 % - 4.9 %
Components96-well polystyrene microplate coated with a monoclonal antibody against CRP
Mouse CRP Standard, lyophilized
CRP Detect Antibody
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers
DescribtionThis assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse ST2. The Mouse ST2/IL-33R ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Suppression of Tumorigenicity 2 (ST2), also known as IL-33R, is an Interleukin-1 receptor family glycoprotein that contributes to Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes. ST2 binds IL-33, a pro-inflammatory IL-1 family cytokine with intracellular and extracellular activities. In addition to its role in promoting mast cell and Th2 dependent inflammation, transmembrane ST2 activation enhances inflammation-associated hypernociception and protects from atherosclerosis and cardiac myocyte hypertrophy. The soluble ST2 isoform is elevated in the serum under inflammatory conditions including allergic asthma, sepsis, trauma, dengue fever, and pulmonary disease. Serum ST2 elevation is also associated with multiple aspects of heart failure including aortic stenosis, congestive cardiomyopathy, and risk of cardiovascular heart failure and death.
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