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MULTI SCIENCES

96 Wells Human Galectin-3 ELISA Kit

96 Wells Human Galectin-3 ELISA Kit

SKU:EK1126

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Product Details

96 Wells Human Galectin-3 ELISA Kit

Brand

MultiSciences

CatNum

70-EK1126

Product Name

Human Galectin-3 ELISA Kit

Customs Name

Human Galectin-3 ELISA Kit

Application

ELISA

Reactivity

Human

Assay Type

Sandwich ELISA

Suitable Sample Type

serum, plasma, cell culture supernates

Format

96-well strip plate

Storage

4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened)

Shipping Condition

4℃

Sample Volume

100 μl

Sensitivity

2.46 pg/ml

Standard Curve Range

62.50 - 4000 pg/ml

Spike Recovery Range

85 % - 105 %

Mean Spike Recovery

1.01

CV of Intra plate

1.7 % - 3.5 %

CV of Inter plate

3.9 % - 4.9 %

Components

96-well polystyrene microplate coated with a monoclonal antibody against Galectin-3

Human Galectin-3 Standard, lyophilized

Galectin-3 Detect Antibody

Standard Diluent

Streptavidin-HRP

Assay Buffer (10×)

Substrate (TMB)

Stop Solution

Washing Buffer (20×)

Plate Covers

Describtion

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human Galectin-3. The Human Galectin-3 is for research use only. Not for diagnostic or therapeutic procedures.

Galectin-3 is a protein that belongs to the lectin family, it is expressed in the nucleus, cytoplasm, mitochondrion, cell surface, and extracellular space. Galectin-3 has an affinity for β-galactosides and exhibits antimicrobial activity against bacteria and fungi. It is involved in many biological processes: cell adhesion, cell activation and chemoattraction, cell growth and differentiation, cell cycle, and apoptosis. Given galectin-3’s broad biological functionality, it has been demonstrated to be involved in cancer, inflammation and fibrosis, heart disease, and stroke.

A correlation between galectin-3 expression levels and various types of fibrosis has been found. Galectin-3 is upregulated in cases of liver fibrosis, renal fibrosis, and idiopathic pulmonary fibrosis (IPF). Elevated levels of galectin-3 have been found to be significantly associated with higher risk of death in both acute decompensated heart failure and chronic heart failure populations. Also, galectin-3 has been suggested to play important roles in cancer metastasis.