MultiSciences

EK1252

Human Bcl-2 ELISA Kit

Human Bcl-2 ELISA Kit

ELISA

Human

SDS - EK1252

Sandwich ELISA

serum, plasma, cell culture supernates

96-well strip plate

4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened)

4℃

20 μl

50.25 pg/ml

468.75 - 30000 pg/ml

90% - 110%

0.99

4.0% - 4.9%

2.4% - 4.7%

96-well polystyrene microplate coated with a monoclonal antibody against Bcl-2
Human Bcl-2 Standard, lyophilized
Bcl-2 Detect Antibody
Standard Diluent
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human Bcl-2. The Human Bcl-2 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
B-cell lymphoma 2 (Bcl-2), is the founding member of the Bcl-2 family of regulator proteins that regulate cell death (apoptosis), by either inducing (pro-apoptotic) or inhibiting (anti-apoptotic) apoptosis. Bcl-2 is specifically considered an important anti-apoptotic protein and is thus classified as an oncogene. Bcl-2 is known to regulate mitochondrial dynamics, and is involved in the regulation of mitochondrial fusion and fission. Additionally, in pancreatic beta-cells, Bcl-2 and Bcl-XL are known to be involved in controlling metabolic activity and insulin secretion.
Damage to the Bcl-2 gene has been identified as a cause of a number of cancers, including melanoma, breast, prostate, chronic lymphocytic leukemia, and lung cancer, and a possible cause of schizophrenia and autoimmunity. It is also a cause of resistance to cancer treatments.