MultiSciences

70-EK1165

Human BMP-7 ELISA Kit

Human BMP-7 ELISA Kit

ELISA

Human

Sandwich ELISA

serum, plasma, cell culture supernates

96-well strip plate

4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened)

4℃

20 μl

2.06 pg/ml

7.81 - 500 pg/ml

74 % - 120 %

0.98

4.4 % - 5.3 %

2.3 % - 4.9 %

96-well polystyrene microplate coated with a monoclonal antibody against BMP-7
Human BMP-7 Standard, lyophilized
BMP-7 Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human BMP-7. The Human BMP-7 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Bone morphogenetic protein 7 (BMP-7) expressed in the brain, kidneys and bladder is a member of the TGF-β superfamily. It plays a key role in the transformation of mesenchymal cells into bone and cartilage. BMP-7 induces the phosphorylation of SMAD1 and SMAD5, which in turn induce transcription of numerous osteogenic genes. It has been demonstrated that BMP7 treatment is sufficient to induce all of the genetic markers of osteoblast differentiation in many cell types.
BMP-7 has the potential for treatment of chronic kidney disease. BMP-7 administration has been proposed as a possible treatment for human infertility due to poor response to FSH treatment. A BMP-7 therapy for obesity in humans may be developed as a result.