MULTI SCIENCES
Human CA125/MUC16 ELISA Kit
Human CA125/MUC16 ELISA Kit
SKU:EK1274
Product Details
| Factory Name | MultiSciences |
|---|---|
| Product Code | 70-EK1274-96 |
| CatNum | EK1274-96 |
| Product Name | Human CA125/MUC16 ELISA Kit |
| Customs Name | Human CA125/MUC16 ELISA Kit |
| Product Spec | 96 T |
| Type | ELISA Kit |
| Application | ELISA |
| Reactivity | Human |
| SDS | SDS - EK1274 |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 50 μl |
| Sensitivity | 0.41 pg/ml |
| Standard Curve Range | 15.63 - 1000 pg/ml |
| Spike Recovery Range | 92 % - 117 % |
| Mean Spike Recovery | 105% |
| CV of Intra plate | 3.2 % - 4.1 % |
| CV of Inter plate | 1.7 % - 2.7 % |
| Components |
96-well polystyrene microplate coated with a monoclonal antibody against CA125 Human CA125 Standard, lyophilized CA125 Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution Washing Buffer (20×) Plate Covers |
| Describtion |
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human CA125/MUC16. The Human CA125/MUC16 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Cancer antigen 125, carcinoma antigen 125, or carbohydrate antigen 125(CA125) also known as mucin 16 or MUC16, is a protein that in humans is encoded by the MUC16 gene. MUC16 is a member of the mucin family glycoproteins. It is a component of the ocular surface, the respiratory tract and the female reproductive tract epithelia. Since MUC16 is highly glycosylated it creates a hydrophilic environment that acts as a lubricating barrier against foreign particles and infectious agents on the apical membrane of epithelial cells. Also, the cytoplasmic tail of MUC16 has been shown to interact with cytoskeleton by binding members of the ERM protein family. The expression of mucin 16 has been shown to be altered in dry eye, cystic fibrosis, and several types of cancers. |
