MULTI SCIENCES
Human CD258/LIGHT/TNFSF14 ELISA Kit Plate
Human CD258/LIGHT/TNFSF14 ELISA Kit Plate
SKU:EK1217
Product Details
| Brand | MultiSciences |
|---|---|
| CatNum | 70-EK1217 |
| Product Name | Human CD258/LIGHT/TNFSF14 ELISA Kit |
| Customs Name | Human CD258/LIGHT/TNFSF14 ELISA Kit |
| Application | ELISA |
| Reactivity | Human |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 20 μl |
| Sensitivity | 22.26 pg/ml |
| Standard Curve Range | 312.50 - 20000 pg/ml |
| Spike Recovery Range | 80 % - 118 % |
| Mean Spike Recovery | 0.91 |
| CV of Intra plate | 3.6 % - 4.8 % |
| CV of Inter plate | 2.6 % - 4.5 % |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against CD258 Human CD258 Standard, lyophilized CD258 Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution Washing Buffer (20×) Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human CD258. The HumanCD258/LIGHT/TNFSF14 ELISA is for research use only. Not for diagnostic or therapeutic procedures. CD258, also known as LIGHT and tumor necrosis factor superfamily member 14 (TNFSF14), is a secreted protein of the TNF superfamily. It is a type II transmembrane protein expressed on activated T cells and immature dendritic cells and recognized by herpesvirus entry mediator (HVEM), as well as decoy receptor 3. This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, trigger apoptosis of various tumor cells and block viral entry. It is also reported to prevent TNF alpha mediated apoptosis in primary hepatocyte. In addition, CD258 has been implicated in T cell development and homeostasis, dendritic cell maturation, and atherogenesis and may play a prominent role in diseases involving T cells such as graft versus host disease (GVHD) and autoimmune conditions. |
