|Product Name||Human CTGF ELISA Kit|
|Customs Name||Human CTGF ELISA Kit|
|Assay Type||Sandwich ELISA|
|Suitable Sample Type||serum, plasma, cell culture supernates|
|Format||96-well strip plate|
|Storage||4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)|
|Sample Volume||50 μl|
|Standard Curve Range||62.50 - 4000 pg/ml|
|Spike Recovery Range||88 % - 115 %|
|Mean Spike Recovery||1.03|
|CV of Intra plate||6.3 % - 7.5 %|
|CV of Inter plate||4.9 % - 6.7 %|
|Components||96-well polystyrene microplate coated with a monoclonal antibody against CTGF
Human CTGF Standard, lyophilized
CTGF Detect Antibody
Assay Buffer (10×)
washing Buffer (20×)
|Describtion||This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human CTGF. The Human CTGF ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Connective tissue growth factor (CTGF, CCN2) is a matricellular protein of the CCN family. has The extracellular part of CTGF includes four conserved, cysteine-rich domains: the insulin-like growth factor binding protein (IGFBP) domain, the von Willebrand type C repeats (vWC) domain, the thrombospondin type 1 repeat (TSR) domain, and a C-terminal domain (CT) with a cysteine knot motif. CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, and tissue wound repair. It is thought that CTGF can cooperate with TGF-β to induce sustained fibrosis and to exacerbate extracellular matrix production in association other fibrosis-inducing conditions.
Monitoring of CTGF levels in serum provides more detailed insights in several pathological situations such as malignancies, diabetic nephropathy, retinopathy, fibrosis, arthritis, pancreatic cancer and cardiovascular diseases.