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MULTI SCIENCES

Human CXCL13/BLC/BCA-1 ELISA Assay Kit

Human CXCL13/BLC/BCA-1 ELISA Assay Kit

SKU:EK1105

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Product Details

Human CXCL13/BLC/BCA-1 ELISA Assay Kit

Brand MultiSciences
CatNum 70-EK1105
Product Name Human CXCL13/BLC/BCA-1 ELISA Kit
Customs Name Human CXCL13/BLC/BCA-1 ELISA Kit
Application ELISA
Reactivity Human
Assay Type Sandwich ELISA
Suitable Sample Type serum, plasma, cell culture supernates
Format 96-well strip plate
Storage 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition 4℃
Sample Volume 20 μl
Sensitivity 4.86 pg/ml
Standard Curve Range 31.25 - 2000 pg/ml
Spike Recovery Range 87 % - 114 %
Mean Spike Recovery 0.99
CV of Intra plate 1.3 % - 6.5 %
CV of Inter plate 2.7 % - 4.9 %
Release Date 2015/11/26
Components 96-well polystyrene microplate coated with a monoclonal antibody against CXCL13
Human CXCL13 Standard, lyophilized
CXCL13 Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers
Describtion This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human CXCL13. The Human CXCL13/BLC/BCA-1 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Chemokine (C-X-C motif) ligand 13 (CXCL13), also known as B lymphocyte chemoattractant (BLC) or B cell-attracting chemokine 1 (BCA-1) is expressed highly in the liver, spleen, lymph nodes, and gut of humans. It is selectively chemotactic for B cells belonging to both the B-1 and B-2 subsets, and elicits its effects by interacting with chemokine receptor CXCR5. CXCL13 and its receptor CXCR5 control the organization of B cells within follicles of lymphoid tissues.
In T lymphocytes, CXCL13 expression is thought to reflect a germinal center origin of the T cell, particularly a subset of T cells called follicular B helper T cells (or Tfh cells). Hence, expression of CXCL13 in T-cell lymphomas, such as Angioimmunoblastic T-cell Lymphoma, is thought to reflect a germinal center origin of the neoplastic T-cells.