|Suitable Sample Type||serum, plasma, cell culture supernates|
|Format||96-well strip plate|
|Storage||4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened)|
|Sample Volume||100 μl|
|Standard Curve Range||3.13 - 200 pg/ml|
|Spike Recovery Range||81% - 105%|
|Mean Spike Recovery||0.98|
|CV of Intra plate||4.3% - 5.7%|
|CV of Inter plate||5.5% - 7.3%|
|Components||96-well polystyrene microplate coated with a monoclonal antibody against CXCL16
Human CXCL16 Standard, lyophilized
CXCL16 Detect Antibody
Assay Buffer (10×)
Washing Buffer (20×)
|Describtion||This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human CXCL16. The Human CXCL16 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Chemokine (C-X-C motif) ligand 16 (CXCL16) is a small cytokine belonging to the CXC chemokine family. It is a type I membrane protein with 254 amino acids. The gene for human CXCL16 is located on chromosome 17.CXCL16 is produced by dendritic cells found in the T cell zones of lymphoid organs, and by cells found in the red pulp of the spleen.Expression of CXCL16 is induced by the inflammatory cytokines IFN-gamma and TNF-alpha. CXCL16 interacts with the chemokine receptor CXCR6, also known as Bonzo. The administration of folinic acid, which forces the methylation of CXCL 16, induces high levels of methylation of the CXCL 16 gene promoter in colon, ileum and lung and causes iNKT cells accumulation in these tissues.