MULTI SCIENCES
Human CXCL3/GRO-γ ELISA Kit
Human CXCL3/GRO-γ ELISA Kit
SKU:EK1265
Product Details
Factory Name | MultiSciences |
---|---|
Product Code | 70-EK1265-96 |
CatNum | EK1265-96 |
Product Name | Human CXCL3/GRO-γ ELISA Kit |
Customs Name | Human CXCL3/GRO-γ ELISA Kit |
Product Spec | 96T |
SalePrice | 3200 |
Type | ELISA Kit |
Application | ELISA |
Reactivity | Human |
Modality | NoData |
Assay Type | Sandwich ELISA |
Suitable Sample Type | serum, plasma, cell culture supernates |
Format | 96-well strip plate |
Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
Shipping Condition | 4℃ |
Sensitivity | 0.24 pg/ml |
Standard Curve Range | 1.56-100 pg/ml |
Spike Recovery Range | 86%-105% |
Mean Spike Recovery | 0.95 |
CV of Intra plate | 2.3% - 11.5% |
CV of Inter plate | 2.6% - 5.5% |
Components |
96-well polystyrene microplate (12 strips of 8 wells) coated with a monoclonal antibody against human CXCL3 Human CXCL3 Standard, lyophilized CXCL3 Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution Washing Buffer (20×) Adhesive Films |
Describtion | CXCL1, CXCL2, and CXCL3, also known respectively as GRO alpha, GRO beta (MIP-2 alpha) and GRO gamma (MIP-2 beta), are members of the CXC subfamily of chemokines. Mature CXCL1/2/3 proteins bind with high affinity to the IL-8 receptor type B and are potent neutrophil attractants and activators. Chemokines act primarily on leukocytes, regulating their trafficking. In general, chemokine α family members preferentially chemoattract and activate neutrophils. Recombinant Human GRO-γ is a 7.9 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. Mature human CXCL3 (aa 35-107) shares 70% and 74% amino acid (aa) sequence identity with mouse and rat CXCL3, respectively. CXCL3 plays a key role in monocyte migration and adhesion through its interaction with the CXCR2 receptor. |
