MULTI SCIENCES
Human FGFR2/CD332 Protein A ELISA Kit
Human FGFR2/CD332 Protein A ELISA Kit
SKU:EK1242
Product Details
| Brand | MultiSciences |
|---|---|
| CatNum | 70-EK1242 |
| Product Name | Human FGFR2/CD332 ELISA Kit |
| Customs Name | Human FGFR2/CD332 ELISA Kit |
| Application | ELISA |
| Reactivity | Human |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 50 μl |
| Sensitivity | 4.14 pg/ml |
| Standard Curve Range | 31.25 - 2000 pg/ml |
| Spike Recovery Range | 74 % - 124 % |
| Mean Spike Recovery | 1.07 |
| CV of Intra plate | 3.0 % - 7.6 % |
| CV of Inter plate | 5.1 % - 6.8 % |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against FGFR2 Human FGFR2 Standard, lyophilized FGFR2 Detect Antibody Standard Diluent Assay Buffer (10×) Substrate (TMB) Stop Solution Washing Buffer (20×) Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human FGFR2. The Human FGFR2/CD332 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Fibroblast growth factor receptor 2 (FGFR2), also known as CD332, is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. This protein consists of an extracellular region composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. FGFR2 has important roles in embryonic development and tissue repair, especially bone and blood vessels. Mutations are associated with numerous medical conditions that include abnormal bone development (e.g. craniosynostosis syndromes) and cancer. |
