MULTI SCIENCES
Human FGFR4/CD334 ELISA Kit Distributor
Human FGFR4/CD334 ELISA Kit Distributor
SKU:EK1237
Product Details
| Brand | MultiSciences |
|---|---|
| CatNum | 70-EK1237 |
| Product Name | Human FGFR4/CD334 ELISA Kit |
| Customs Name | Human FGFR4/CD334 ELISA Kit |
| Application | ELISA |
| Reactivity | Human |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 20 μl |
| Sensitivity | 12.76 pg/ml |
| Standard Curve Range | 156.25 - 10000 pg/ml |
| Spike Recovery Range | 70 % - 96 % |
| Mean Spike Recovery | 0.85 |
| CV of Intra plate | 1.8 % - 3.5 % |
| CV of Inter plate | 1.9 % - 5.8 % |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against FGFR4 Human FGFR4 Standard, lyophilized FGFR4 Detect Antibody Standard Diluent Assay Buffer (10×) Substrate (TMB) Stop Solution Washing Buffer (20×) Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human FGFR4/CD334. The Human FGFR4/CD334 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Fibroblast growth factor receptor 4 (FGFR4), also known as CD334, is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis. |
