|Product Name||Human GRO-β ELISA Kit|
|SDS||SDS - EK1264|
|Assay Type||Sandwich ELISA|
|Suitable Sample Type||serum, plasma, cell culture supernates|
|Format||96-well strip plate|
|Storage||4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened)|
|Sample Volume||10 μl|
|Standard Curve Range||4.688 - 300 pg/ml|
|Spike Recovery Range||85 % - 110 %|
|Mean Spike Recovery||99%|
|CV of Intra plate||4.8 % - 5.0 %|
|CV of Inter plate||3.8 % - 4.7 %|
|Components||96-well polystyrene microplate coated with a monoclonal antibody against GRO-β
Human GRO-β Standard, lyophilized
GRO-β Detect Antibody
Assay Buffer (10×)
Washing Buffer (20×)
|Describtion||This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human GRO-β. The Human GRO-β ELISA is for research use only. Not for diagnostic or therapeutic procedures.
The Growth-regulated oncogene beta (GRO-β), also known as chemokine (C-X-C motif) ligand 2 (CXCL2) is a member of the CXC chemokine superfamily. The GRO-β, also called MIP-2 in mouse and CINC-3 in rat. Human GRO-β is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. And GRO-β is produced by a variety of cell types including monocytes and macrophages at sites of inflammation and is chemotactic for granulocytes, including neutrophils.
The GRO-β plays an important role in inflammation and wound healing process. As extensive research continued, researchers realized that the GRO gene was one of oncogenes. And its expression product, GRO-β, was also found to be very important in angiogenesis, tumorigeness, tastasis, and interaction between tumor and immune cells.