MULTI SCIENCES
Human IGFBP-1 ELISA Kit Distributor
Human IGFBP-1 ELISA Kit Distributor
SKU:EK1255
Product Details
| CatNum | EK1255 |
|---|---|
| Product Name | Human IGFBP-1 ELISA Kit |
| Customs Name | Human IGFBP-1 ELISA Kit |
| Application | ELISA |
| Reactivity | Human |
| SDS | SDS - EK1255 |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 10 μl |
| Sensitivity | 0.93 pg/ml |
| Standard Curve Range | 31.25 - 2000 pg/ml |
| Spike Recovery Range | 83% - 118% |
| Mean Spike Recovery | 1.01 |
| CV of Intra plate | 4.8% - 5.2% |
| CV of Inter plate | 3.0% - 5.0% |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against IGFBP-1 Human IGFBP-1Standard, lyophilized IGFBP-1 Detect Antibody Standard Diluent Assay Buffer (10×) Substrate (TMB) Stop Solution Washing Buffer (20×) Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IGFBP-1. The Human IGFBP-1 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Insulin-like growth factor-binding protein 1 (IGFBP-1) also known as placental protein 12 (PP12) is a protein that in humans is encoded by the IGFBP1 gene. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. IGFBPs modulate the biological activities of IGF proteins.Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. High IGFBP-1 may be a marker of a catabolic state. Research shows that women with higher IGFBP-1 were more likely to have a low relative muscle mass. Higher IGFBP-1/IGF-1 serum ratio is significantly associated with poor prognosis in nasopharyngeal carcinoma(NPC) patients. Local IGFBP1 level was reported to affect the development of coronary artery plaque. |
