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MULTI SCIENCES

Human IGFBP-4 ELISA Kit

Human IGFBP-4 ELISA Kit

SKU:EK1277

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Product Details

Human IGFBP-4 ELISA Kit

Factory Name MultiSciences
Product Code 70-EK1277-96
CatNum EK1277
Product Name Human IGFBP-4 ELISA Kit
Customs Name Human IGFBP-4 ELISA Kit
Product Spec 96 T
Type ELISA Kit
Application ELISA
Reactivity Human
SDS SDS - EK1277
Assay Type Sandwich ELISA
Suitable Sample Type serum, plasma, cell culture supernates
Format 96-well strip plate
Storage 4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition 4℃
Sample Volume 20 μl
Sensitivity 6.51 pg/ml
Standard Curve Range 125 - 8000 pg/ml
Spike Recovery Range 81% - 115%
Mean Spike Recovery 94%
CV of Intra plate 2.9 % - 4.0 %
CV of Inter plate 2.8% - 4.0 %
Components

96-well polystyrene microplate coated with a monoclonal antibody against IGFBP-4

Human IGFBP-4 Standard, lyophilized

IGFBP-4 Detect Antibody

Streptavidin-HRP

Assay Buffer (10×)

Substrate (TMB)

Stop Solution

Washing Buffer (20×)

Plate Covers

Describtion

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IGFBP-4. The Human IGFBP-4 ELISA is for research use only. Not for diagnostic or therapeutic procedures.

Insulin-like growth factor binding protein 4 (IGFBP-4) is a 24-kDa protein , The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.

The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-RP). IGFBP-4 inhibits IGF-I action in vitro and is the most abundant IGFBP in the rodent arterial wall. Expression of IGFBP-4 mRNA in nontransgenic littermates was maximal in liver and kidne