MULTI SCIENCES
Human IL-11 ELISA Kit
Human IL-11 ELISA Kit
SKU:EK111
Product Details
Brand | MultiSciences |
---|---|
CatNum | 70-EK111 |
Product Name | Human IL-11 ELISA Kit |
Specification | 96 T |
Application | ELISA |
Reactivity | Human |
Assay Type | Sandwich ELISA |
Suitable Sample Type | serum, plasma, cell culture supernates |
Format | 96-well strip plate |
Storage | 4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened) |
Shipping Condition | 4℃ |
Sample Volume | 20 μl |
Sensitivity | 5.01 pg/ml |
Standard Curve Range | 62.50 - 4000 pg/ml |
Spike Recovery Range | 84 % -118 % |
Mean Spike Recovery | 0.99 |
CV of Intra plate | 5.6 % - 8.3 % |
CV of Inter plate | 4.4 % - 7.1 % |
Components |
96-well polystyrene microplate coated with a monoclonal antibody against IL-11 Human IL-11 Standard, lyophilized IL-11 Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution washing Buffer (20×) Plate Covers |
Describtion |
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IL-11. The Human IL-11 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Interleukin 11 (IL-11) is a multifunctional cytokine first isolated in 1990 from bone marrow-derived stromal cells. It is a member of the IL-6-type cytokine family, distinguished based on their use of the common co-receptor gp130. IL-11 is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation. IL-11 causes bone-resorption. It stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. As a signaling molecule, IL-11 has a variety of functions include placentation and to some extent of decidualization. IL-11 has been expressed to have a role during implantation of the blastocyst in the endometrium of the uterus. IL-11 is manufactured using recombinant DNA technology and is marketed as a protein therapeutic called oprelvekin, for the prevention of severe thrombocytopenia in cancer patients. |
