MULTI SCIENCES
Human IL-13 Antibody ELISA Kit
Human IL-13 Antibody ELISA Kit
SKU:EK113
Product Details
| Brand | MultiSciences |
|---|---|
| CatNum | 70-EK113 |
Product Name |
Human IL-13 ELISA Kit |
Customs Name |
Human IL-13 ELISA Kit |
Application |
ELISA |
Reactivity |
Human |
Assay Type |
Sandwich ELISA |
Suitable Sample Type |
serum, plasma, cell culture supernates |
Format |
96-well strip plate |
Storage |
4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
Shipping Condition |
4℃ |
Sample Volume |
50 μl |
Sensitivity |
0.90 pg/ml |
Standard Curve Range |
7.81 - 500 pg/ml |
Spike Recovery Range |
82 % - 110 % |
Mean Spike Recovery |
0.98 |
CV of Intra plate |
1.7 % - 2.0 % |
CV of Inter plate |
2.2 % - 4.1 % |
Components |
96-well polystyrene microplate coated with a monoclonal antibody against IL-13 Human IL-13 Standard, lyophilized IL-13 Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution washing Buffer (20×) Plate Covers |
| Describtion |
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IL-13. The Human IL-13 ELISA is for research use only. Not for diagnostic or therapeutic procedures. IL-13 is located on chromosome 5q31 with a length of 1.4kb. IL-13 and IL-4 exhibit a 30% of sequence similarity and have a similar structure. IL-13 is cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells. IL-13 has effects on immune cells that are similar to those of the closely related cytokine IL-4. Although IL-13 is associated primarily with the induction of airway disease, it also has anti-inflammatory properties. IL-13 is known to induce changes in hematopoietic cells, but these effects are probably less important than that of IL-4. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. IL-13 specifically induces physiological changes in parasitized organs that are required to expel the offending organisms or their products. IL-13 induces many features of allergic lung disease, including airway hyperresponsiveness, goblet cellmetaplasia and mucus hypersecretion, which all contribute to airway obstruction. Furthermore, IL-13 inhibits HIV-1 replication in primary culture-derived macrophages and represents a candidate cytokine for the suppression of HIV infection within monocytes and macrophages in vivo. |
