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MULTI SCIENCES

Human IL-17E/IL-25 ELISA Kit

Human IL-17E/IL-25 ELISA Kit

SKU:EK1179

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Product Details

Human IL-17E/IL-25 ELISA Kit

Brand MultiSciences
CatNum 70-EK1179
Product Name Human IL-17E/IL-25 ELISA Kit
Specification  96 T
Application ELISA
Reactivity Human
Assay Type Sandwich ELISA
Suitable Sample Type serum, plasma, cell culture supernates
Format 96-well strip plate
Storage 4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition 4℃
Sample Volume 20 μl
Sensitivity 2.39 pg/ml
Standard Curve Range 93.75 - 6000 pg/ml
Spike Recovery Range 80 % - 116 %
Mean Spike Recovery 96%
CV of Intra plate 2.8 % - 4.7 %
CV of Inter plate 2.7 % - 4.2 %
Components

96-well polystyrene microplate coated with a monoclonal antibody against IL-17E

Human IL-17E Standard, lyophilized

IL-17E Detect Antibody

Standard Diluent

Streptavidin-HRP

Assay Buffer (10×)

Substrate (TMB)

Stop Solution

Washing Buffer (20×)

Plate Covers

Describtion

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IL-17E. The Human IL-17E/IL-25 ELISA is for research use only. Not for diagnostic or therapeutic procedures.

Interleukin 17E (IL-17E), also known as IL-25, is a cytokine that belongs to the IL-17 cytokine family and is secreted by type 2 helper T cells (Th2) and mast cells. It shares the sequence similarity with IL-17. This cytokine can induce NF-κB activation, and stimulate the production of IL-8. Both this cytokine and IL-17B are ligands for the cytokine receptor IL-17RB. Studies in mice suggested that this cytokine may be a proinflammatory cytokine favoring Th2-type immune response. 

IL-17E induces the production of other cytokines, including IL-4, IL-5 and IL-13 in multiple tissues, which stimulate the expansion of eosinophils. This cytokine is an important molecule controlling immunity of the gut and has been implicated in chronic inflammation associated with the gastrointestinal tract. IL-17E can kill some types of breast cancer cells.