MULTI SCIENCES
Human IL-1β ELISA Kit
Human IL-1β ELISA Kit
SKU:EK101B
Product Details
Factory Name | MultiSciences |
---|---|
Product Code | 70-EK101B-96 |
CatNum | EK101B-96 |
Product Name |
Human IL-1β ELISA Kit |
Customs Name |
Human IL-1β ELISA Kit |
Product Spec | 96T |
Type | ELISA Kit |
Application |
ELISA |
Reactivity |
Human |
SDS | SDS - EK101B |
Assay Type | Sandwich ELISA |
Suitable Sample Type |
serum, plasma, cell culture supernates |
Format |
96-well strip plate |
Storage |
4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
Shipping Condition |
4℃ |
Sample Volume |
20 μl |
Sensitivity |
0.15pg/ml |
Standard Curve Range |
3.91 - 250 pg/ml |
Spike Recovery Range |
94 % - 113 % |
Mean Spike Recovery |
105% |
CV of Intra plate |
4.7 % - 6.1 % |
CV of Inter plate |
4.1 % - 6.6 % |
Components |
96-well polystyrene microplate coated with a monoclonal antibody against IL-1β Human IL-1β Standard, lyophilized IL-1β Detect Antibody Standard Diluent Assay Buffer (10×) SubstHumane (TMB) Stop Solution Washing Buffer (20×) Plate Covers |
Describtion | Interleukin-1 (IL-1) is an extracellular peptide of 17 kDa that designates two proteins, IL-1α and IL-1β. IL-1β is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The interleukin-1 (IL-1) species represent an important family of biologically active mono nuclear cell-derived proteins which are involved in inflammatory reactions and in immune responses.Increased production of IL-1β causes a number of different autoinflammatory syndromes, most notably the monogenic conditions referred to as CAPS, due to mutations in the inflammasome receptor NLRP3 which triggers processing of IL-1β. This kit is designed to detect the cleaved mature form and uncleaved pro-form of human IL-1β. |
