MultiSciences

70-EK101BHS

EK101BHS

Human IL-1β High Sensitivity ELISA Kit

Human IL-1β High Sensitivity ELISA Kit

ELISA

Human

SDS - EK101BHS

Sandwich ELISA

serum, plasma, cell culture supernates

96-well strip plate

4℃ (unopened)standard stored at -20℃，others  stored at 4℃ (opened)

4℃

20 μl

0.02 pg/ml

0.19 - 12 pg/ml

93 % - 112 %

1.02

4.5 % - 5.6 %

2.3 % - 8.9 %

96-well polystyrene microplate coated with  a monoclonal antibody against IL-1β
Human IL-1β Standard, lyophilized
IL-1β Detect Antibody
Standard Diluent
Streptavidin-HRP
Amplification Reagent Concentrate
Amplification Diluent
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers

This assay employs the quantitative  sandwich enzyme immunoassay technique for the quantitative detection of human  IL-1β. The Human IL-1β ELISA is for research use only. Not for diagnostic or therapeutic  procedures.
Interleukin-1 (IL-1) is an extracellular peptide of 17 kDa that designates  two proteins, IL-1α and IL-1β.  IL-1β is produced by activated macrophages as a  proprotein, which is proteolytically processed to its active form by caspase  1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory  response, and is involved in a variety of cellular activities, including cell  proliferation, differentiation, and apoptosis.The interleukin-1 (IL-1)  species represent an important family of biologically active mono nuclear  cell-derived proteins which are involved in inflammatory reactions and in  immune responses.
Increased production of IL-1β causes a number of  different autoinflammatory syndromes, most notably the monogenic conditions  referred to as CAPS, due to mutations in the inflammasome receptor NLRP3  which triggers processing of IL-1β.