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MULTI SCIENCES

Human IL-20 Protein A ELISA Kit

Human IL-20 Protein A ELISA Kit

SKU:EK120

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Product Details

Human IL-20 Protein A ELISA Kit

Brand

MultiSciences

Cat Num

70-EK120

Product Name

Human IL-20 ELISA Kit

Customs Name

Human IL-20 ELISA Kit

Application

ELISA

Reactivity

Human

Assay Type

Sandwich ELISA

Suitable Sample Type

serum, plasma, cell culture supernates

Format

96-well strip plate

Storage

4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened)

Shipping Condition

4℃

Sample Volume

50 μl

Sensitivity

11.87 pg/ml

Standard Curve Range

46.88 - 3000 pg/ml

Spike Recovery Range

78 % - 121 %

Mean Spike Recovery

0.96

CV of Intra plate

2.9 % - 4.2 %

CV of Inter plate

2.8 % - 4.7 %

Components

96-well polystyrene microplate coated with a monoclonal antibody against IL-20
Human IL-20 Standard, lyophilized
IL-20 Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
washing Buffer (20×)
Plate Covers

Describtion

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IL-20. The Human IL-20 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Human interleukin 20 (IL-20) is a protein belonging to the IL-10 family of cytokines. It exhibits approximately 28% amino acid (aa) identity with IL-10 and 76% aa identity with mouse IL-20. IL-20 is produced by activated keratinocytes and monocytes and transmits an intracellular signal through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. In addition, IL-20 regulates proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. IL-20 also causes cell expansion of multipotential hematopoietic progenitor cells. The over-expression of both human and mouse forms of IL-20 results in keratinocyte hyperproliferation, abnormal epidermal differentiation, and neonatal lethality.