MULTI SCIENCES
Human IL-21 ELISA Kit Distributor
Human IL-21 ELISA Kit Distributor
SKU:EK121
Product Details
| Brand | MultiSciences |
|---|---|
| CatNum | 70-EK121 |
| Product Name | Human IL-21 ELISA Kit |
| Customs Name | Human IL-21 ELISA Kit |
| Application | ELISA |
| Reactivity | Human |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 50 μl |
| Sensitivity | 11.99 pg/ml |
| Standard Curve Range | 62.50 - 4000 pg/ml |
| Spike Recovery Range | 87 % - 112 % |
| Mean Spike Recovery | 1.02 |
| CV of Intra plate | 4.5 % - 5.6 % |
| CV of Inter plate | 7.2 % - 7.8 % |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against IL-21 Human IL-21 Standard, lyophilized IL-21 Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution washing Buffer (20×) Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IL-21. The Human IL-21 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Interleukin-21 (IL-21) is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells that can destroy virally infected or cancerous cells.This cytokine induces cell division/proliferation in its target cells. IL-21 is expressed in activated human CD4+ T cells but not in most other tissues.In addition, IL-21 expression is up-regulated in Th2 and Th17 subsets of T helper cells, as well as T follicular cells. Furthermore IL-21 is expressed in NK T cells regulating the function of these cells. IL-21 has pathologic function in immune-inflammatory diseases. Data suggest the existence of a positive autocrine loop that could help to amplify and stabilize IL-21-driven, T cell-mediated responses. Moreover, it has antitumour activity and may have a role in the development of autoimmunity. IL-21 may have therapeutic potentials as an antitumor agent in the clinic. |
