MULTI SCIENCES
Human IL-23 ELISA Kit Distributor
Human IL-23 ELISA Kit Distributor
SKU:EK123
Product Details
| Brand | MultiSciences |
|---|---|
| CatNum | 70-EK123 |
| Product Name | Human IL-23 ELISA Kit |
| Customs Name | Human IL-23 ELISA Kit |
| Application | ELISA |
| Reactivity | Human |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 50 μl |
| Sensitivity | 1.82 pg/ml |
| Standard Curve Range | 31.25 - 2000 pg/ml |
| Spike Recovery Range | 86 % - 110 % |
| Mean Spike Recovery | 0.99 |
| CV of Intra plate | 3.4 % - 5.3 % |
| CV of Inter plate | 3.4 % - 4.8 % |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against IL-23 Human IL-23 Standard, lyophilized IL-23 Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution washing Buffer (20×) Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IL-23. The Human IL-23 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Interleukin 23 (IL-23) is a heterodimeric cytokine that is related to IL-12. IL-23 is a heterodimeric cytokine composed of an IL-12p40 subunit that is shared with IL-12 and the IL-23p19 subunit. A functional receptor for IL-23 (the IL-23 receptor) has been identified and is composed of IL-12Rβ1 and IL-23R. Human IL-23 has biological properties which are less distinct from human IL-12; human IL-23 induces proliferation of memory T cells and induces moderate levels of IFN-γ production by na?ve and memory T cells, as compared to IL-12. IL-23 effects on IL-17-producing T cells may also enhance the development of several models of autoimmune disease including experimental allergic encephalomyelitis (EAE), collagen-induced arthritis (CIA), colitis, and diabetes. IL-23 may also play a role in increased tumor growth associated with chronic inflammation. In humans, IL-23 has been found upregulated in several pathologies with dysregulated immune function including psoriasis, Crohn's disease, and multiple sclerosis. |
