MULTI SCIENCES
Human IL-29 ELISA Kit For Protein Quantification
Human IL-29 ELISA Kit For Protein Quantification
SKU:EK129
Product Details
| Brand | MultiSciences |
|---|---|
| CatNum | 70-EK129 |
| Product Name | Human IL-29 ELISA Kit |
| Customs Name | Human IL-29 ELISA Kit |
| Application | ELISA |
| Reactivity | Human |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 20 μl |
| Sensitivity | 0.12 pg/ml |
| Standard Curve Range | 15.63 - 1000 pg/ml |
| Spike Recovery Range | 87 % - 101 % |
| Mean Spike Recovery | 0.93 |
| CV of Intra plate | 4.6 % - 4.7 % |
| CV of Inter plate | 3.1 % - 5.6 % |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against IL-29 Human IL-29 Standard, lyophilized IL-29 Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution washing Buffer (20×) Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IL-29. The Human IL-29 ELISA is for research use only. Not for diagnostic or therapeutic procedures. The IL-29 gene is found on chromosome 19 in humans. It is also known as IFN-λ1 and is highly similar in amino acid sequence to the IL-28, the other type III interferon. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL-29 has significant antiviral activity and immunoregulatory properties and appears to inhibit T helper-2 (Th2) responses regarding inhibition of IL-13 production, compared with IL-4 or IL-5. IL-29 inhibits virus replication by inducing a cellular antiviral response similar to that activated by IFN-α/β. However, because it binds to a unique receptor, this cytokine may function cooperatively with IFN-α/β or IFN-γ during natural infections to inhibit virus replication, and might also be useful therapeutically in combination with other cytokines to treat chronic viral infections such as hepatitis C (HCV).The antiviral activities of IL-29 include the upregulation of MHC Class I expression on the cell surface and the expression of PKR. The ligand/receptor complex seems to signal through the Jak-STAT pathway. IL-29 is not present in the mouse genome. |
