|Product Name||Human MMP-1 ELISA Kit|
|Customs Name||Human MMP-1 ELISA Kit|
|Assay Type||Sandwich ELISA|
|Suitable Sample Type||serum, plasma, cell culture supernates|
|Format||96-well strip plate|
|Storage||4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)|
|Sample Volume||20 μl|
|Standard Curve Range||156.3 - 10000 pg/ml|
|Spike Recovery Range||83 % - 115 %|
|Mean Spike Recovery||1.07|
|CV of Intra plate||1.9 % - 2.3 %|
|CV of Inter plate||5.2 % - 7.9 %|
|Components||96-well polystyrene microplate coated with a monoclonal antibody against MMP-1
Human MMP-1 Standard, lyophilized
MMP-1 Detect Antibody
Assay Buffer (10×)
Washing Buffer (20×)
|Describtion||This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human MMP-1. The Human MMP-1 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Matrix metalloproteinase-1 (MMP-1) also known as interstitial collagenase and fibroblast collagenase is an enzyme that in humans is encoded by the MMP1 gene. MMP-1 has an archetypal structure consisting of a pre-domain, a pro-domain, a catalytic domain, a linker region and a hemopexin-like domain.
MMPs are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Specifically, MMP-1 breaks down the interstitial collagens, types I, II, and III. Mechanical force may increase the expression of MMP1 in human periodontal ligament cells. MMP1 has been shown to interact with CD49b.
This kit is designed to measure total MMP-1 (natural and recombinant human active and pro-MMP-1).