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MULTI SCIENCES

Human MMP-3 ELISA Kit Distributor

Human MMP-3 ELISA Kit Distributor

SKU:EK1M03

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Product Details

Human MMP-3 ELISA Kit Distributor

Brand MultiSciences
CatNum 70-EK1M03
Product Name Human MMP-3 ELISA Kit
Customs Name Human MMP-3 ELISA Kit
Application ELISA
Reactivity Human
Assay Type Sandwich ELISA
Suitable Sample Type serum, plasma, cell culture supernates
Format 96-well strip plate
Storage 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition 4℃
Sample Volume 50 μl (prediluted)
Sensitivity 0.30 pg/ml
Standard Curve Range 31.25 - 2000 pg/ml
Spike Recovery Range 95 % - 105 %
Mean Spike Recovery 1.01
CV of Intra plate 4.0 % - 4.9 %
CV of Inter plate 4.2 % - 9.0 %
Components 96-well polystyrene microplate coated with a monoclonal antibody against MMP-3
Human MMP-3 Standard, lyophilized
MMP-3 Detect Antibody
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
washing Buffer (20×)
Plate Covers
Describtion This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human MMP-3. The Human MMP-3 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Matrix metalloproteinase-3 (MMP-3) also known as Stromelysin-1 is an enzyme that in humans is encoded by the MMP3 gene. Expression of MMP3 is primarily regulated at the level of transcription, where the promoter of the gene responds to various stimuli, including growth factors, cytokines, tumor promoters, and oncogene products. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. Nuclear MMP3 functions as a transcription factor and a proteinase.
This kit is designed to measure total MMP-3 (natural and recombinant human active and pro-MMP-3).