MultiSciences

70-EK1194

Human OSMR ELISA Kit

Human OSMR ELISA Kit

ELISA

Human

Sandwich ELISA

serum, plasma, cell culture supernates

96-well strip plate

4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened)

4℃

10 μl

21.54 pg/ml

234.38 - 15000 pg/ml

80 % -105 %

0.94

2.6 % - 3.6 %

2.4 % - 2.5 %

96-well polystyrene microplate coated with a monoclonal antibody against OSMR
Human OSMR Standard, lyophilized
OSMR Detect Antibody
Standard Diluent
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human OSMR. The Human OSMR ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Oncostatin-M-specific receptor subunit beta, also known as OSMR, is a member of the type I cytokine receptor family. OSMR contains four fibronectin type-III domains and is expressed at relatively high levels in all neural cells as well as fibroblast, epithelial and a variety of tumor celllines.
This protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Defects in OSMR are the cause of amyloidosis type 9 which is a hereditary primary amyloidosis characterized by localized cutaneous amyloid deposition.