MULTI SCIENCES
Human P-Selectin ELISA Kit Distributor
Human P-Selectin ELISA Kit Distributor
SKU:EK186
Product Details
| Brand | MultiSciences |
|---|---|
| CatNum | 70-EK186 |
| Product Name | Human P-Selectin ELISA Kit |
| Customs Name | Human P-Selectin ELISA Kit |
| Application | ELISA |
| Reactivity | Human |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 20 μl (prediluted) |
| Sensitivity | 1.11 pg/ml |
| Standard Curve Range | 78.13 - 5000 pg/ml |
| Spike Recovery Range | 88 % - 106 % |
| Mean Spike Recovery | 0.96 |
| CV of Intra plate | 5.4 % - 9.0 % |
| CV of Inter plate | 5.3 % - 7.8 % |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against sP-Selectin Human sP-Selectin Standard, lyophilized sP-Selectin Detect Antibody Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution washing Buffer (20×) Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human sP-Selectin. The Human sP-Selectin ELISA is for research use only. Not for diagnostic or therapeutic procedures. P-Selectin, also known as CD62P, Granule Membrane Protein 140 (GMP-140), and Platelet Activation-Dependent Granule to External Membrane Protein (PADGEM), is a cell surface glycoprotein that plays a critical role in the migration of lymphocytes into tissues. P-Selectin consists of an EGF-like domain, an NH2-terminal lectin type C domain, a transmembrane domain, a short cytoplasmic domain, and nine complement control domains. Evidence indicates that P-Selectin is mobilized to the cell surface in response to a variety of inflammatory or thrombogenic agents.Circulating soluble P-Selectin is slightly smaller than native P-Selectin. Evidence suggests that the majority of sP-Selectin lacks the transmembrane anchoring domain due to its alternatively spliced mRNA. Monitoring of sP-Selectin levels in serum provides more detailed insights in several pathological situations such as thrombotic thrombocytopenic purpura and haemolytic uremic syndrome. |
