MultiSciences

70-EK1160

Human Relaxin-2 ELISA Kit

Human Relaxin-2 ELISA Kit

ELISA

Human

Sandwich ELISA

serum, plasma, cell culture supernates

96-well strip plate

4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened)

4℃

50 μl

1.01 pg/ml

7.81 - 500 pg/ml

80 % - 119%

1

4.3 % - 7.2 %

2.2 % - 5.4 %

96-well polystyrene microplate coated with a monoclonal antibody against Relaxin-2
Human Relaxin-2 Standard, lyophilized
Relaxin-2 Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human Relaxin-2. The Human Relaxin-2 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Human Relaxin-2 is synthesized and secreted as a preprohormone that is 18 kDa in size and 185 amino acids in length. It is a peptide hormone best known for its important physiological roles during pregnancy. The role of relaxin in pregnancy physiology differs considerably between mammals. In humans and other primates, relaxin does play a role in pregnancy, albeit an earlier role of modulating endometrial physiology during implantation. In rodents there is a major pre-labor surge in circulating relaxin levels, corresponding to its role in parturition; however, in humans and other primates, the serum levels of relaxin are highest during the first trimester. In women, the ovarian corpus luteum is the source of circulating Relaxin-2. It should be noted that Relaxin-2 is also present in males and is synthesized by non-reproductive organs such as the kidney, heart, and lungs suggesting a more global contribution for this hormone. Relaxin-2 initiates its pleiotropic effects through multiple pathways on a variety of cell types. It confers activity by binding to the leucine-rich G protein-coupled receptor LRG7, and with significantly less affinity to LRG8.