MULTI SCIENCES
Human Serpin E1/PAI-1 Assay ELISA Kit
Human Serpin E1/PAI-1 Assay ELISA Kit
SKU:EK1136
Product Details
| Brand | MultiSciences |
|---|---|
| CatNum | 70-EK1136 |
Product Name |
Human Serpin E1/PAI-1 ELISA Kit |
Customs Name |
Human Serpin E1/PAI-1 ELISA Kit |
Application |
ELISA |
Reactivity |
Human |
Assay Type |
Sandwich ELISA |
Suitable Sample Type |
serum, plasma, cell culture supernates |
Format |
96-well strip plate |
Storage |
4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
Shipping Condition |
4℃ |
Sample Volume |
100 μl |
Sensitivity |
1.53 pg/ml |
Standard Curve Range |
312.50 - 20000 pg/ml |
Spike Recovery Range |
80 % - 118 % |
Mean Spike Recovery |
0.9 |
CV of Intra plate |
2.3 % - 4.8 % |
CV of Inter plate |
2.3 % - 2.6 % |
Components |
96-well polystyrene microplate coated with a monoclonal antibody against PAI-1 Human PAI-1 Standard, lyophilized PAI-1 Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution Washing Buffer (20×) Plate Covers |
| Describtion |
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human PAI-1. The Human Serpin E1/PAI-1 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Serpin E1, also known as plasminogen activator inhibitor-1 (PAI-1), is mainly produced by the endothelium (cells lining blood vessels), but is also secreted by other tissue types, such as adipose tissue. It is a serine protease inhibitor (serpin) that functions as the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), the activators of plasminogen and hence fibrinolysis. PAI-1 is present in increased levels in various disease states (such as a number of forms of cancer), as well as in obesity and the metabolic syndrome. It has been linked to the increased occurrence of thrombosis in patients with these conditions. |
