MULTI SCIENCES
Human SICAM-3/CD50 ELISA Kit
Human SICAM-3/CD50 ELISA Kit
SKU:EK1312
Product Details
| Factory Name | MultiSciences |
|---|---|
| Product Code | 70-EK1312-96 |
| CatNum | EK1312-96 |
| Product Name | Human sICAM-3/CD50 ELISA Kit |
| Customs Name | Human sICAM-3/CD50 ELISA Kit |
| Product Spec | 96T |
| SalePrice | 3200 |
| Type | ELISA Kit |
| Application | ELISA |
| Reactivity | Human |
| Modality | NoData |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sensitivity | 5.09 pg/ml |
| Standard Curve Range | 125-8000 pg/ml |
| Spike Recovery Range | 77%-112% |
| Mean Spike Recovery | 0.93 |
| CV of Intra plate | 1.6% - 6.2% |
| CV of Inter plate | 2.5% - 3.9% |
| Components |
96-well polystyrene microplate (12 strips of 8 wells) coated with a monoclonal antibody against human sICAM-3 Human sICAM-3 Standard, lyophilized sICAM-3 Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution Washing Buffer (20×) Adhesive Films |
| Describtion | Intercellular Adhesion Molecule-3 (ICAM-3), also known as CD50, is a member of the immunoglobulin superfamily, can bind the leukocyte integrins LFA-1 (CD11a/CD18) and αd/β2. ICAM?3 is expressed on leukocytes and epidermal Langerhans cells. ICAM-3 is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells.CD50 molecule can play a role in developing functionally mature T lymphocytes and its expression increases during the maturation process of T lymphocytes. |
