MULTI SCIENCES
Human STNF RII/TNFRSF1B Antibody ELISA Kit
Human STNF RII/TNFRSF1B Antibody ELISA Kit
SKU:EK1123
Product Details
| Brand | MultiSciences |
|---|---|
| CatNum | 70-EK1123 |
| Product Name | Human sTNF RII/TNFRSF1B ELISA Kit |
| Customs Name | Human sTNF RII/TNFRSF1B ELISA Kit |
| Application | ELISA |
| Reactivity | Human |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 100 μl (prediluted) |
| Sensitivity | 0.08 pg/ml |
| Standard Curve Range | 7.81 - 500 pg/ml |
| Spike Recovery Range | 103 % - 118 % |
| Mean Spike Recovery | 1.13 |
| CV of Intra plate | 2.4 % - 5.4 % |
| CV of Inter plate | 2.4 % - 4.3 % |
| Release Date | 2015/11/26 |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against sTNF RII Human sTNF RII Standard, lyophilized sTNF RII Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution Washing Buffer (20×) Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human sTNF RII. The Human sTNF RII/TNFRSF1B is for research use only. Not for diagnostic or therapeutic procedures. Tumor necrosis factor receptor II (TNFRII), also known as tumor necrosis factor receptor superfamily member 1B (TNFRSF1B), is a membrane receptor that binds tumor necrosis factor-alpha (TNF-α). This protein and TNF-receptor I form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF - receptor signalling is unknown, however, c-IAP1 is thoughtto potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF- receptor - associated factor 2 (TRAF2), which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. |
