|Product Name||Human TGF-beta1 ELISA Kit|
|Customs Name||Human TGF-beta1 ELISA Kit|
|Assay Type||Sandwich ELISA|
|Suitable Sample Type||serum, plasma, cell culture supernates|
|Format||96-well strip plate|
|Storage||4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)|
|Sample Volume||50 μl (prediluted)|
|Standard Curve Range||31.25 - 2000 pg/ml|
|Spike Recovery Range||83 % - 117 %|
|Mean Spike Recovery||0.99|
|CV of Intra plate||2.0 % - 5.3 %|
|CV of Inter plate||4.1 % - 6.0 %|
|Components||96-well polystyrene microplate coated with a monoclonal antibody against TGF-β1
Human TGF-β1 Standard, lyophilized
TGF-β1 Detect Antibody
Assay Buffer (10×)
washing Buffer (20×)
|Describtion||This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human TGF-β1. The Human TGF-β1 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Transforming growth factor beta 1 (TGF-β1) is a polypeptide member of the transforming growth factor beta superfamily of cytokines that performs many cellular functions, including the control of cell growth,cell proliferation, cell differentiation and apoptosis. TGF-βs are a multifunctional set peptides that controlsproliferation, differentiation, and other functions in many cell types. TGF-βs act synergistically with TGFA in inducingtransformation. It also acts as a negative autocrine growth factor. Dysregulation of TGF-β activation and signaling may result in apoptosis. Many cells synthesize TGF-β and almost all of them have specific receptors for this peptide. TGF-β1, TGF-β2 , and TGF-β3 all function through the same receptor signaling systems. TGF-β1 plays an important role in controlling the immune system, and shows different activities on different types of cell, or cells at different developmental stages. Most immune cells (orleukocytes) secrete TGF-β1.
TGF-β1 is related to cancer, autoimmune diseases, liver diseases, kidney diseases, diabetes, cardiovascular diseases, asthma, chronic obstructive pulmonary disorder (COPD), cystic fibrosis (CF) and so on.