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Human VEGF R1/FLT-1 ELISA Kit Plate

Human VEGF R1/FLT-1 ELISA Kit Plate


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Human VEGF R1/FLT-1 ELISA Kit Plate

Brand MultiSciences
CatNum 70-EK1117
Product Name Human VEGF R1/Flt-1 ELISA Kit
Customs Name Human VEGF R1/Flt-1 ELISA Kit
Application ELISA
Reactivity Human
Assay Type Sandwich ELISA
Suitable Sample Type serum, plasma, cell culture supernates
Format 96-well strip plate
Storage 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition 4℃
Sample Volume 20 μl
Sensitivity 6.99 pg/ml
Standard Curve Range 156.25 - 10000 pg/ml
Spike Recovery Range 96 % - 114 %
Mean Spike Recovery 0.99
CV of Intra plate 4.6 % - 5.5 %
CV of Inter plate 2.9 % - 4.6 %
Components 96-well polystyrene microplate coated with a monoclonal antibody against VEGF R1
Human VEGF R1 Standard, lyophilized
VEGF R1 Detect Antibody
Standard Diluent
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers
Describtion This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human VEGF R1. The Human VEGF R1/Flt-1 ELISA is for research use only. Not for diagnostic or therapeutic procedures.

Vascular endothelial growth factor receptor-1 (VEGF R1), also known as Flt-1, is a receptor tyrosine kinase (RTK) specific for the angiogenic factors VEGF (VEGF-A), PlGF, and VEGF-B. There are two forms: membrane - bound (mbVEGFR) and soluble (sVEGFR), depending on alternative splicing.

Experimental and clinical administrations of sVEGF R1 have been employed successfully in the prevention of neovasculogenesis and tumor growth. The serum/plasma level of sVEGF R1 may vary by pathology, and may have prognostic value. It has been suggested that sVEGF R1 levels should be presented alongside VEGF levels in experimental and pathological conditions. High levels of sVEGF R1 reportedly occur in the plasma during pregnancy and in patients with essential hypertension. Significantly lower levels have been observed in the plasma of patientswith cardiovascular disease and in smokers.